Dean of Research and Industry Relations
and the Department of Pharmaceutical Engineering
Positions:
Dean of Research and Industry Relations
Recent publications:
1. Inhibiting MARCH5/Mfn2 Signaling as an Alternative Strategy to Protect Cardiomyocytes from Hypoxia-Induced Mitochondrial Dysfunction, F. Habrat Zoabi, M. Zerihun, R. Lizarovich, C. D. Torre, L Davis, O Ertracht, M. Barsheshet, S. Atar, D. E. Shalev, M. De Zotti, H. Senderowitz, N. Qvit, Computational and Structural Biotechnology Journal.
2. Simple Hydroxybenzene Molecules as Thermally Stable Catalysts, O. Agazani, D. Boas, V. Shankar Tiwari, O. Cohen, D. E. Shalev*, M. Reches*, ChemSystemsChem 2025 doi: 10.1002/syst.202500006
3. Spontaneous Formation of Sustainable Antifreeze Coating by Peptide Self-Assembly, M. Kaganovich, E. Gibeon, A. Shilling Bakalinsky, D. E. Shalev, I. Braslavsky and M. Reches, ACS Applied Materials & Interfaces 2025.
4. EspH utilizes a phosphoinositide binding motif to interact with the host plasma membrane and multiple Rab GTPases, I. Nandi, R. P. Ramachandran, D. E. Shalev, D. Schneidman-Duhovny, R. Shtuhin-Rahav, N. Melamed-Book, I. Rosenshine, B. Aroeti, Gut Microbes 2024 Jan-Dec;16(1):2400575. doi: 10.1080/19490976.2024.2400575
5. A Multifunctional Drug Delivery System Based on Switchable Peptide-Stabilized Emulsions, D. Boas, A. van Teijlingen, Z. Shpilt, D. E. Shalev*, E. Y. Tshuva*, T. Tuttle*, M. Reches*, Chem 2024 https://doi.org/10.1016/j.chempr.2024.02.003
6. Self-assembly of a Dipeptide with a Reduced Amount of Copper into Antifungal and Antibacterial Particles, M. Kaganovich, M. Taha, U. Zig, E, Tshuva, D. E. Shalev, A. Gamiliel, M. Reches Biomacromolecules 2024 25, 1018, DOI10.1021/acs.biomac.3c01092
7. Studying peptide-metal ion complex structures by solution-state NMR, Shalev, DE Int J Mol Sci 2022 23(24). doi: 10.3390/ijms232415957
8. Structural insights into the role of the WW2 domain on tandem WW-PPxY motif interactions of oxidoreductase WWOX, S. Rotem-Bamberger, J. Fahoum, K. Keinan-Adamsky, T. Tsaban, O. Avraham, D. E. Shalev, J. H., and O, Schueler-Furman, J Biol Chem 2022 298, 102145, doi.org/10.1016/j.jbc.2022.102145 (IF 5.485, Q1, 5 citations) Took part in experimental design.
9. An edible erodible semi-interpenetrating polymer network as a microcapsule shell to protect probiotic bacteria during reconstitution of powdered infant formula at elevated temperature, A. Penhasi, I. Baluashvili, D. E. Shalev, J Appl Polymer Sci 2022 139:e52201 https://doi.org/10.1002/app.52201
10. Determining the Structure and Binding Mechanism of Oxytocin-Cu2+ Complex using Paramagnetic Relaxation Enhancement NMR Analysis, Alshanski, I, Shalev DE*, Yitzchaik, S*, Hurevich, M*, J Biol InorgChem 2021 26, 809-815 doi: 10.1007/s00775-021-01897-1
11. Diselenide Crosslinks for Enhanced and Simplified Oxidative Protein Folding, R. Mousa, T. Hidmi, S. Pomyalov, S. Lansky, L. Khouri, D. E. Shalev, G. Shoham, N. Metanis, Commun Chem 2021, 4, 30. doi.org/10.1038/s42004-021-00463-9
12. Cyclizing painkillers: development of backbone cyclic TAPS analogs, A. Talhami, A. Swed, S, Hess, S. Greenberg, O. Ovadia, D. Rosenthal, D.E. Shalev, M. Hurevich, A. Hoffman, C. Gilon, Front Chem. 2020, 10, 1030. DOI: 10.3389/fchem.2020.532577
13. Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins, T Tayri-Wilk, M Slavin, J Zamel, A Blass, S Cohen, A Motzik, Xue Sun, DE Shalev, O Ram, and N Kalisman, Nature Comm 2020, 11(1), 1-19. doi.org/10.1038/s41467-020-16935-w
15. A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids. Samarasimhareddy M, Shamir M, Shalev DE, Hurevich M, Friedler A. Front Chem. 2020;8:405. doi: 10.3389/fchem.2020.00405
15. High modulus thermoplastic segmented polyurethane/poly(L-lactide) blends as potential candidates for structural implantable drug delivery systems: I. Structure-properties relationship study, A Penhasi, A Gertler, I Baluashvili, O Elzinaty, DE Shalev, J Appl Polym Sci. 2020; e49517. doi: 10.1002/app.49517
16. A novel nicotine pectinate salt formulated in a specific time-controlled delivery system: A new approach for colon-targeted nicotine release, Penhasi A, Gomberg M, Shalev DE, Journal of Drug Delivery Science and Technology. 2020 doi: 10.1016/j.jddst.2020.101583
Prof. Deborah E. Shalev
Faculty member of the Department of Pharmaceutical Engineering
Email:
[email protected]