Dr. Aiman Abu Ammar
Senior Lecturer
Phone: +97226591835
Email: aimanab@jce.ac.il
Positions:
Academic Head of the Pre-Academic Programs (Mechinot)
Member, Steering Committee for Arab Students
Member, Internal Appointing Committee
Member, Teaching Committee
Coordinator of Final Projects
Departmental Representative in the Academia – Industry Forum
Research Interests:
Multi-disciplinary research with a focus on developing localized drug delivery systems using nanotechnology, for controlled release of lipophilic drugs
Incorporating biodegradable drug-loaded nanoparticles and nanofibers into medical devices
Developing biomimetic adhesive surfaces utilizing biocompatible and biodegradable polymers for drug delivery and biomedical applications
Selected Publication (last 5 years):
- Biswas, N.; Abu Ammar, A.,; Frušić-Zlotkin, M.; Adi-Hen, N.; Lehman-Katabi, Y.; Levi-Kalisman, Y.; Nassar, T.; Benita, S., 2021. Biodistribution and Efficacy of the Anticancer Drug, Oxaliplatin Palmitate Acetate, in Mice. International Journal of Pharmaceutics, 120740.
- Abdel-Haq, M., Alyan, R., Abd-Rbo, K., Kasem, H. and Abu Ammar, A., 2021. Biomimetic clotrimazole-loaded PLGA films with enhanced adhesiveness for controlled drug release. International Journal of Pharmaceutics, 601, p.120578.
- Abu Ammar, A., Abdel-Haq, M., Abd-Rbo, K. and Kasem, H., 2021. Developing Novel Poly (Lactic-Co-Glycolic Acid)(PLGA) Films with Enhanced Adhesion Capacity by Biomimetic Mushroom-Shaped Microstructures. Biotribology, p.100184.
- Kabha, A., Bukchin-Tihomirov, A., Shlomi, I., Abu Ammar, A., Bidder, M., Amiel, G. and Zussman, E., Biodegradable Controlled-Release Device for Localized Chemotherapeutic Treatment of Bladder Cancer. ACS biomaterials science & engineering.
- Jahshan, F., Abu Ammar, A., Ertracht, O., Eisenbach, N., Daoud, A., Sela, E., Zussman, E., Fichtman, B., Harel, A. and Gruber, M., 2021. Local Delivery of Mometasone Furoate from an Eluting Endotracheal Tube Reduces Airway Morbidity Following Long-Term Animal Intubation. ACS Applied Bio Materials, 4, 5, 4131–4139.
- Far, J., Abdel-Haq, M., Gruber, M. and Abu Ammar, A., 2020. Developing Biodegradable Nanoparticles Loaded with Mometasone Furoate for Potential Nasal Drug Delivery. ACS omega, 5(13), pp.7432-7439.
- Jahshan, F., Ertracht, O., Eisenbach, N., Daoud, A., Sela, E., Atar, S., Abu Ammar, A. and Gruber, M., 2020. A novel rat model for tracheal mucosal damage assessment of following long term intubation. International journal of pediatric otorhinolaryngology, 128, p.109738.
- Abu Ammar, A., Nasereddin, A., Ereqat, S., Dan-Goor, M., Jaffe, C.L., Zussman, E. and Abdeen, Z., 2019. Amphotericin B-loaded nanoparticles for local treatment of cutaneous leishmaniasis. Drug delivery and translational research, 9(1), pp.76-84.
- Jahshan, F., Ertracht, O., Abu Ammar, A., Ronen, O., Srouji, S., Apel-Sarid, L., Eisenbach, N., Atar, S., Sela, E. and Gruber, M., 2018. A novel rat model for assessment of laryngotracheal injury following transoral intubation. International journal of pediatric otorhinolaryngology, 113, pp.4-10.
- Abu Ammar, A., Gruber, M., Martin, P., Stern, O., Jahshan, F., Ertracht, O., Sela, E., Srouji, S. and Zussman, E., 2018. Local delivery of mometasone furoate from an eluting endotracheal tube. Journal of Controlled Release, 272, pp.54-61.
- Khamaysi, I., Abu Ammar, A., Vasilyev, G., Arinstein, A., Chowers, Y. and Zussman, E., 2017. Differentiation of pancreatic cyst types by analysis of rheological behavior of pancreatic cyst fluid. Scientific reports, 7(1), pp.1-8.
- Lancuški, A., Abu Ammar, A., Avrahami, R., Vilensky, R., Vasilyev, G. and Zussman, E., 2017. Design of starch-formate compound fibers as encapsulation platform for biotherapeutics. Carbohydrate polymers, 158, pp.68-76.
- Abu Ammar, A., Raveendran, R., Gibson, D., Nassar, T. and Benita, S., 2016. A lipophilic Pt (IV) oxaliplatin derivative enhances antitumor activity. Journal of medicinal chemistry, 59(19), pp.9035-9046.
Patents:
Benita, S., Nassar, T., Gibson, D. and Abu Ammar, A.; “Pt (IV) derivatives and nanocarriers comprising them”, 2019, U.S. Patent No. 10,239,903.
Zussman, E., Abu Ammar, A., Gruber, M.; "Electrospun coated medical devices", WO2019138412A1, July 18, 2019.
Abu Ammar, A., Kasem, H.; "Bioadhesive films and methods of use thereof", U.S. Provisional Patent Appl. 63/112,209, November 11, 2020.