{"id":4126,"date":"2024-06-16T14:26:18","date_gmt":"2024-06-16T11:26:18","guid":{"rendered":"https:\/\/www.jce.ac.il\/en\/?page_id=4126"},"modified":"2024-06-16T14:27:01","modified_gmt":"2024-06-16T11:27:01","slug":"prof-deborah-e-shalev","status":"publish","type":"page","link":"https:\/\/www.jce.ac.il\/en\/prof-deborah-e-shalev\/","title":{"rendered":"Prof. Deborah E. Shalev"},"content":{"rendered":"

\"\"Associate Professor<\/p>\n

Tel: +972-2-658-1830
\nMail:\u00a0debbie@jce.ac.il<\/a><\/p>\n

Positions:<\/strong><\/p>\n

Chairman of the Committee of Internationalization<\/p>\n

Research Interests:<\/strong><\/p>\n

Structural analysis of peptide, protein and polymer systems by nuclear magnetic resonance (NMR) and other spectroscopic and thermoanalytical methods<\/p>\n

Representative Publications:<\/strong><\/p>\n

1. Cyclizing painkillers: development of backbone cyclic TAPS analogs, A. Talhami, A. Swed, S, Hess, S. Greenberg, O. Ovadia, D. Rosenthal, D.E. Shalev, M. Hurevich, A. Hoffman, C. Gilon, Front Chem<\/em>. 2020<\/strong>, 10<\/em>, 1030. DOI: 10.3389\/fchem.2020.532577<\/p>\n

2. Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins, T Tayri-Wilk, M Slavin, J Zamel, A Blass, S Cohen, A Motzik, Xue Sun, DE Shalev, O Ram, and N Kalisman, Nature Comm<\/em> 2020<\/strong> , 11<\/em>(1), 1-19. doi.org\/10.1038\/s41467-020-16935-w<\/p>\n

3. A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids. Samarasimhareddy M, Shamir M, Shalev DE, Hurevich M, Friedler A. Front Chem<\/em>. 2020<\/strong>;8:405. doi: 10.3389\/fchem.2020.00405.<\/p>\n

4. High modulus thermoplastic segmented polyurethane\/poly(L-lactide) blends as potential candidates for structural implantable drug delivery systems: I. Structure-properties relationship study, A Penhasi, A Gertler, I Baluashvili, O Elzinaty, DE Shalev, J Appl Polym Sci<\/em>. 2020<\/strong>; e49517. doi: 10.1002\/app.49517 \u2013 chosen for Cover figure<\/em><\/p>\n

5. A novel nicotine pectinate salt formulated in a specific time-controlled delivery system: A new approach for colon-targeted nicotine release, Penhasi A, Gomberg M, Shalev DE, Journal of Drug Delivery Science and Technology<\/em>. 2020<\/strong> doi: 10.1016\/j.jddst.2020.101583<\/p>\n

6. Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin. Weil-Ktorza O, Rege N, Lansky S, Shalev DE, Shoham G, Weiss MA, Metanis N., Chemistry<\/em>. 2019<\/strong>; 25:8513-8521 doi: 10.1002\/chem.201900892 \u2013 chosen for Cover figure<\/em><\/p>\n

7. Tailoring the self-assembly of a tripeptide for the formation of antimicrobial surfaces. Nir S, Zanuy D, Zada T, Agazani O, Aleman C, Shalev DE, Reches M. Nanoscale<\/em>. 2019<\/strong>;11(18):8752-8759 \u2013 chosen for inside front cover figure<\/em><\/p>\n

8. The Bacterial Extracellular Matrix Protein TapA Is a Two-Domain Partially Disordered Protein. Abbasi R, Mousa R, Dekel N, Amartely H, Danieli T, Lebendiker M, Levi-Kalisman Y, Shalev DE, Metanis N, Chai L. Chembiochem<\/em>. 2018; 20:355-359. doi: 10.1002\/cbic.201800634 \u2013 chosen for cover figure<\/em><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Associate Professor Tel: +972-2-658-1830 Mail:\u00a0debbie@jce.ac.il Positions: Chairman of the Committee of Internationalization Research Interests: Structural analysis of peptide, protein and polymer systems by nuclear magnetic resonance (NMR) and other spectroscopic and thermoanalytical methods Representative Publications: 1. Cyclizing painkillers: development of\u05dc\u05db\u05ea\u05d1\u05d4 \u05d4\u05de\u05dc\u05d0\u05d4…<\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/modules-in-content.php","meta":{"_acf_changed":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"class_list":["post-4126","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nProf. Deborah E. 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