Dr. Debbie Shalev

Dr. Debbie Shalev
Senior Lecturer

Department of Pharmaceutical Engineering
The Jerusalem College of Engineering
POB 3566, Jerusalem 91035, Israel
How to get to the JCE

Positions:
Deputy Head of the Department of Pharmaceutical Engineering
Senior Lecturer
Tel: +972-2-658-8000 Ext: 8312
Fax: +972-2-659-1800
Mail: debbie@.jce.ac.il
Web: www.jce.ac.il

Research Interests:

• Nuclear magnetic resonance studies of peptides
• Intrinsically disordered and amyloidogenic peptides
• Spectroscopic investigation of microemulsions

Representative Publications:

1. Do food microemulsions and dietary mixed micelles interact? S.Rozner, D.E. Shalev, A.I. Shames, M.F. Ottaviani, A. Aserin, N. Garti – 2010 Colloids and Surfaces B: Biointerfaces 77, 22-30.

2. Structural Disorder in the HIV-1 Vif Protein and Interaction-Dependent Gain of Structure, T.H. Reingewertz, D.E. Shalev and A. Friedler - 2010 Protein and Peptide Letters 17, 988-98..

3. Mechanism of action of the HIV-1 integrase inhibitory peptide LEDGF 361-370 2010 Z. Hayouka, A. Levin, M. Maes, E. Hadas, D.E. Shalev, D.J. Volsky, A. Loyter, A. Friedler, Biochemical and Biophysical Research Communications  394, 260-265.

4. Complete Phenotypic Recovery of an Alzheimer's Disease Model by a Quinone-Tryptophan Hybrid Aggregation Inhibitor, R. Scherzer-Attali, R. Pellarin, M. Convertino, A Frydman-Marom, M. Levy-Sakin, D. E. Shalev, A. Caflisch, E. Gazit and D. Segal – 2010 Plos ONE 5.

5. NMR characterization of a Cu(i)-bound peptide model of copper metallochaperones: Insights on the role of methionine. M.S. Shoshan, D.E. Shalev, W. Adriaens, M. Merkx, T.M. Hackeng, E.Y. Tshuva,  Chem Commun (Camb). 2011 47(22):6407-9.